Centrophenoxine is synthesized from the naturally occurring DMAE chemical. DMAE has been shown to have a positive impact on mood and cognition, but there are some disputes about its method of action. Some people believe that it should be considered a precursor to Acetylcholine. However, others believe that this is not accurate due to the fact that the broken down choline molecules that result from DMAE have not been proven to efficiently cross the blood-brain barrier. Centrophenoxine is believed to be a more efficient and bioavailable form of DMAE with different and more advanced effects.
Mechanism of Action
In order to understand Centrophenoxine’s mechanism of action, it is first necessary to have a clear understanding of the importance of Acetylcholine. Increasing the receptor uptake and overall level of this naturally occurring neurotransmitter has been strongly suggested to influence cognitive-functioning.
With this in mind, Centrophenoxine capsules may help to improve choline or Acetylcholine levels through direct or indirect means. However, not all choline may become converted into Acetylcholine, and the levels of this conversion may also vary. It is unclear exactly how Centrophenoxine interacts with Acetylcholine or other neurotransmitters.
It is unclear exactly what may cause Centrophenoxine to modulate Acetylcholine, however it is believed that this supplement is superior to DMAE in this area. It is believed that Centropheoxine capsules are much higher in bioavailability than DMAE. Overall, it is generally believed that Centrophenoxine enhances cognition, most likely through increasing the activity or availability of certain neurotransmitters within the brain.
There is some unsubstantiated speculation that Centrophenoxine is also able to improve mood by affecting the brain’s level or activity of Dopamine and Serotonin. It is possible that Centrophenoxine capsules can impact multiple neurotransmitter systems therefore leading to multiple mechanisms of action as a nootropic.
Centrophenoxine capsules are known to offer antioxidant benefits. This leads to a reduction of free radicals within the brain, and Centrphenoxine been believed to have higher antioxidant properties than DMAE. Due to this, it is marketed in some areas as an “anti-aging” supplement.
- May Enhance Memory Retention
- Stacks Well with Racetams & Other Nootropics
- Potential Acetylcholine Enhancer
- Brain Antioxidant
Possible Side Effects
In most cases, Centrophenoxine capsules seem to be well tolerated, however this nootropic does have some potential side effects. The most prevalent side effects occur when users take high dosages or combine Centrophenoxine with other substances. Therefore, it is recommended that you speak to your doctor before adding Centrophenoxine into your regimen.
The most commonly experienced side effects of Centrophenoxine capsules include: dizziness, headaches, irritability, gastrointestinal problems, nausea and jaw clenching. If you experience any of these issues, you may be able to correct the situation by reducing your dosage of Centrophenoxine. If you experience any of these or other side effects, consult a doctor immediately. Please be aware that it is possible to experience a rare serious allergic reaction to this supplement.
Centrophenoxine capsules may be a source of Acetylcholine just like Alpha GPC and CDP Choline, and this makes it a popular supplement for stacking. Centrophenoxine capsules are a solid choice for stacking with supplements from the racetam family because the synergistic mixture may heighten cholinergic benefits.
There are pros and cons to choosing Centrophenoxine over CDP Choline or Alpha GPC, and they vary by user. Most people do not use Centrophenoxine as a replacement for CDP or GPC. Centrophenoxine capsules may be synergetic with choline supplements or may potentially cause side effects when stacked depending on the user.
Centrophenoxine capsules are often added to brain health stacks due to their potential to reduce free radicals within the brain. Fish Oil, ALCAR and Alpha-Lipoic Acid are commonly added to a brain anti-oxidant stack in conjunction with Centrophenoxine.
The Pros and Cons of Taking Centrophenoxine Capsules
Some nootropic users prefer the powder version of Centrophenoxine because it is less expensive, however there are many compelling reasons to switch to capsules instead. For example, Centrophenoxine capsules never need to be measured out like powder, and this means that you will save time and energy. Additionally, you will avoid the problems that can be associated with measuring out the wrong powder dose.
Another nice perk that accompanies Centrophenoxine capsules is their lack of any strong taste. Although it has been said to have a sweet taste, some people find it overbearingly “chemically” and bitter.