Sulbutiamine Capsules

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200 mg Capsules

  • Nootropic Stimulant
  • Improves Memory
  • Stacks Well
  • May Help Mood

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Sulbutiamine was developed in Japan as a more efficient version of vitamin B1. Vitamin B1 (thiamine) is an essential nootropic vitamin and this mimics the effects of Thiamine at a more basic level. Sulbutiamine is more efficient than thiamine at crossing the blood brain barrier and therefore much stronger in terms of effects. It brings its own set of unique properties and can be used alone or stacked with other nootropics.

Method of Action

It is believed that sulbutiamine works similarly to thiamine however the effects are greatly enhanced. Thiamine is essential in the body and even more essential for cognitive function because it is used in the biosynthesis of acetylcholine and GABA.  sulbutiamine is believed to have effects on the cholinergic, glutamatergic and dopamine systems which result in its nootropic benefits.

Thiamine is inferior to sulbutimaine in its absorption rate. It is absorbed through the intestines at a poor rate that is often reduced by hindrances like folic deficiency. Having higher concentrations of Thiamine in the digestive tract will also reduce this absorption rate even further. Sulbutiamine is much more lipophilic and is able to dissolve in fats. This not only gives it a better absorption rate but more importantly, increases blood brain barrier efficiency.

Potential Benefits

Sulbutiamine has long been used as an over-the-counter nootropic. Certain studies have pointed it to improving memory function. This is likely due to its influence on acetylcholine and glutamate activity. Influence of D1 dopamine receptor function may also aid in added cognitive benefits.

Sulbutiamine seems to have a mild stimulant effects in some. Many athletes were using it as a legal performance enhancer in sports and it is quite popular in these communities. Sulbutimaine does not seem to affect the other catecholamines other than dopamine so it does not have a tendency to trigger your typical amphetamine-stimulant side effects.


Sulbutiamine seems to have some powerful anti-depressant effects. This may be due to the effects subutiamine has on Dopamine and the D1 receptors. Reports of sulbutiamine and its effects on mood are incredibly common. It can act as a very powerful anti -depressant for short periods of time. These effects commonly recede after recurrent use so sulbutiamine shouldn’t be used primarily as an anti-depressant.

Possible Side Effects

Sulbutiamine has few side effects and is generally well-tolerated however there are still some things to be mindful of. The most common reported side effects are anxiety and irritability. These side effects are more likely to appear in higher than normal doses. Sulbutiamine also seems to promote depression/anxiety in some. If this does occur it is highly recommended to discontinue use. Below is a list of some reported sulbutiamine side-effects.

  • Anxiety
  • Irritability
  • Depression
  • Headaches
  • Nausea
  • Skin Rash


Sulbutiamine has a history of causing tolerance build-up fairly quickly. This is more common to see with the mood boosting and energizing effects of sulbutiamine but some see nootropic actions diminish as well. For this reason, it is great as a “stacked” or “as needed” supplement.

Sulbutiamine does not seem to be addictive however there was one report of an alleged addiction. It does not seem to be an item that is much risk to cause addiction because it is not a psychoactive compound.

Sulbutiamine Stacks

Sulbutiamine is great to stack with racetams. It does not seem to potentiate the effects of racetams but may accent a stack quite nicely by bringing in its own unique properties. In advanced nootropic users, sulbutiamine is a common member in a stack that may be used on and off with the other members.

Sulbutiamine is unique and can accent other nootropics quite well. A great synergistic combination is said to be with pyritinol. This is said to be a great nootropic stack that is not too common. All in all, sulbutiamine is great to stack if you like it. Always try sulbutiamine before using it in a stack to assess your sensitivity and tolerance to the substance.

Pros and Cons of Choosing Sulbutiamine Capsules

Sulbutiamine dapsules make the process of taking this nootropic supplement much easier.  The use of capsules eliminates the need to measure out quantities, as well as no longer having to be concerned with cleanup following dose measuring.  For people that measure out their own capsules, this adds a measure of convenience.  Due to these factors, many people prefer to purchase Sulbutiamine capsules.

The use of any nootropic in powder form makes the creation of stacks easier.  In addition, capsules are more expensive on a weight basis than the same product in powder form, due to the added cost of the components in the capsule as well as the labor to encapsulate.  For those who use standard dosages and do not require special stack mixes, the convenience of using Sulbutiamine in capsule form is worth the price difference for many people, whether they have busy lives or do not desire to constantly measure out powder.

Additional information

Weight 50 g
Dimensions 1.9 × 1.9 × 3.3 in

1 Bottle (60 Caps), 2 Bottles (120 Caps), 3 Bottles (180 Caps)

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