Sulbutiamine is in a class of supplements known as nootropics. Nootropics are known as “smart drugs” because of their cognitive enhancing abilities. Sulbutiamine comes from thiamine, also known as vitamin B1. Because it can cross the blood-brain barrier much easier than thiamine, it is used in a variety of ways.

Once it crosses the blood-brain barrier, the body metabolizes it as thiamine, which the brain then uses to produce the neurotransmitters Acetylcholine (ACh) and GABA.

In addition, it helps facilitate glutamatergic transmissions. Glutamate is the most common neurotransmitter in the central nervous system for excitement. Because of this, it plays a critical role in learning and memory function.

Because sulbutiamine also helps reduce the amount of dopamine released in the prefrontal cortex of the brain, the density of D1 dopamine receptors increases to help boost your overall mood.

Features/ Medical Uses

Initially developed as a treatment for Beriberi, a condition known to cause severe fatigue and lethargy, there are now many medical uses where sulbutiamine could be an effective treatment.

Studies show it is an effective treatment for psychogenic erectile dysfunction. This means men who experience erectile dysfunction because of psychological issues such as depression, anxiety, or stress can get relief. While this may not sound like a big deal, compared to drugs prescribed to treat this condition, sulbutiamine is not only cheaper, but a much safer option.

Sulbutiamine is also commonly prescribed to treat a condition known as asthenia. This disease causes chronic fatigue, but is cerebral in nature.

Due to its memory enhancing abilities, sulbutiamine is also useful in helping patients who suffer from Alzheimer’s disease and schizophrenia.

Benefits

Sulbutiamine has a number of benefits, including:

• Improved memory
• Increased energy levels
• Improved focus
• Improved overall mood

Common Side Effects

No supplement, even safe ones, is free from side effects. Even though this nootropic is highly regarded as safe, and is definitely much safer than stimulant supplements on the market, taking more than the recommended dose could lead to side effects.

At the standard therapeutic dose of 850 mg per day, only mild skin allergies have been reported.

One patient suffering from a lack of energy due to his bipolar disorder, found the supplement so helpful, he ceased using all other medication, and doubled the does of sulbutiamine. This resulted in more severe bipolar disorder symptoms, but no serious health issues have been reported as a result

How to Take Sulbutiamine

This is a nootropic you do not need to take every day. Though it is not really dangerous to take it every day, you can quickly build a tolerance and it could lose its effectiveness within a few fays of regular use. It is best to use this supplement sparingly, to keep the stimulating effect working for you. This nootropic is a much safer alternative to the stimulant supplements on the market today, though you will only see subtle effects.

Sulbutiamine is available in both bulk powder and capsule form. The bulk form is cheaper to buy, but the taste is incredibly foul. If you stick to the powder form, dissolve it in a drink, or buy your own capping machine and produce the capsules yourself. Even with the expense of a capping machine, bulk powder will save you more in the long run.

Dosage Recommendations

The standard recommended dose of sulbutiamine for therapeutic purposes is 850 mg per day, for a person who weighs 150 pounds. If you weigh more, you make need to adjust upward, and if you weigh less, you may need to adjust downward.

Some say you should not exceed 600 mg per day, but even at the 850 mg per day dose, only mild skin reactions have been reported.  To be safe, unless you are using it to treat a specific condition, do not exceed 600 mg per day.

It is best to take this dose once per day, rather than breaking it up into small doses throughout the day. You should feel the effects within an hour after you take it, and the effects will last about five hours before you start to feel the effects diminish.

This supplement is an excellent choice for when you need an extra mental boost—such as when you are studying for a test, or will be giving a presentation and wants to make sure you are sharp. Though not as effective as amphetamine based alternatives, it is much safer and much less likely to cause insomnia.

This information does not come from a medical doctor. It is for educational purposes only, and should not be considered medical advice. Always talk to a doctor before starting this or any other supplement.